Your question: What is in Topamax that causes weight loss?

The active ingredient in Topamax, topiramate, is also the main ingredient in the weight loss drug Qsymia, which is a combination containing phentermine.

What does Topamax do to your metabolism?

Topiramate reduced food intake acutely and increased metabolic rate. There were also significant reductions in leptin, insulin, and corticosterone.

What is the average weight loss on Topamax?

All patients lost a substantial amount of weight on topiramate treatment. The average weight loss was 22 lb (10 kg; range, 8–56 lb [4–25 kg]).

What is the main ingredient in Topamax?

The name of your medicine is TOPAMAX. It contains the active ingredient topiramate. TOPAMAX belongs to a group of medicines known as antiepileptics.

Does Topamax always cause weight loss?

Topamax isn’t approved for weight loss. However, the drug may reduce your appetite, which may lead you to lose weight. In clinical studies, weight loss occurred in 6% to 17% of people who took Topamax. This depended on the dosage and condition treated.

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Does 100mg Topamax cause weight loss?

Migraine prevention – In adults using doses of 50 mg/day for migraine prevention, 6% of patients experienced weight loss, while in the 100 mg/day group, 9% of patients reported weight loss.

Is Topamax an appetite suppressant?

Topamax is FDA approved for migraine prevention, epilepsy treatment and weight loss in combination with phentermine as Qsymia. 7. Topiramate is one of the drugs in the new weight loss medication called Qsymia, which is a mixture of topiramate and phentermine. This is because topiramate suppresses appetite.

Is Topamax a narcotic?

Topamax (generic name: topiramate) is not classified as a controlled substance under the U.S. Controlled Substances Act (CSA). Topamax is an anticonvulsant (seizure) medication, but is also prescribed for other conditions such as prevention of migraine.

What is the best time of day to take Topamax for weight loss?

Take this medicine once a day in the morning, with or without food. Avoid taking this medicine in the evening to prevent trouble sleeping. Swallow the extended-release capsule whole. Do not crush, break, or chew it.

Does Wellbutrin and Topamax cause weight loss?

Although drug companies and independent researchers have studied the weight-loss effects of many of these drugs, including Wellbutrin and Topamax, to date the FDA hasn’t approved any of them for weight loss.

Is Topamax sulfa based?

1. Allergy history and outcome. Although topiramate is a sulfamate compound, none of these patients had history of hypersensitivity to sulfa drugs and it is not clear whether this reaction may be related to sulfa allergy.

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What is the difference between Topamax and gabapentin?

This study showed that topiramate is effective on patients with neuropathic pain and there was no clear difference between topiramate and gabapentin, and in cases of intolerance to gabapentin and other drugs such as antidepressants, topiramate can be replaced in the treatment of neuropathic pain.

Is Topamax a stimulant?

Phentermine is a stimulant and appetite suppressant. Topiramate is an anticonvulsant that has weight loss side effects. The exact mechanism of action for both drugs is unknown.


Combination of
Phentermine Appetite suppressant/stimulant of the amphetamine and phenethylamine class

How fast does Topamax work for weight loss?

It can take some time to see weight loss results from taking Topamax. Some people may not notice a difference until they’ve taken the drug for at least four months, while other people may start to lose weight in their first month of taking it. Weight loss results from topiramate are proven to increase over time.

Can topiramate cause permanent damage?

There are also serious side effects to be aware of when taking Topamax. These side effects usually require hospitalization or medical help, and may result in permanent injury or be life-threatening.

Does weight come back after stopping Topamax?

Conclusions: Loss of body weight is a reversible effect, which at 6 months after TPM discontinuation shows a clear trend to return to baseline values. HOMA-IR is the only predictive factor of weight regain.