Wellbutrin (bupropion) is a prescription medication for depression and smoking cessation. Bupropion can cause weight loss in some people, so it’s sometimes prescribed as a weight loss medication in the form of Contrave (a combination drug of bupropion and naltrexone).
How common is weight loss with bupropion?
Weight changes are considered a side effect for both Wellbutrin XL and Wellbutrin SR. Studies of Wellbutrin XL show that 23% of people taking a dose of 150 to 300 mg per day lost 5 pounds or more. In the same studies, 11% of people gained more than 5 pounds.
Does bupropion suppress appetite?
It stimulates noradrenaline, dopamine, and (less-so) serotonin receptors. This gives you more energy, suppresses your appetite, and enhances your mood.
How long does it take to lose weight on bupropion?
Weight loss with bupropion SR 300 mg/d differed significantly from placebo at 20 weeks. Weight loss with bupropion SR 400 mg/d differed from 300-mg/d doses significantly at 24, 26, 30, 36, and 42 weeks and from placebo at 12, 16, 20, and 24 weeks. The percentage weight loss over 48 weeks.
What is the best antidepressant for weight loss?
Of these three medications, bupropion (Wellbutrin) is the most consistently associated with weight loss. Several studies, including a 2019 meta-analysis of 27 studies, found that bupropion (Wellbutrin) was the only commonly used antidepressant associated with weight loss.
Will I gain weight if I stop taking Wellbutrin?
However, one antidepressant, bupropion (also known as Wellbutrin) seems to have the opposite effect. Weight is often lost while on the drug, and gained after it is stopped.
How do you lose weight on Wellbutrin?
Wellbutrin for Weight Loss Dosage
- Patients may be prescribed a starting dose of Contrave, which is one tablet (naltrexone 8 mg/bupropion 90 mg) once daily in the morning for 1 week.
- This dosage is then increased at week 2 to 1 tablet twice daily, administered in the morning and evening.
Does bupropion give you energy?
Response and effectiveness. When bupropion is used for depression, improvements in sleep, energy, or appetite may be apparent within the first 1-2 weeks. Depressed mood or motivation may take up to 6-8 weeks to fully improve.
What does bupropion do to your body?
Bupropion is an antidepressant medication that works in the brain. It is approved for the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and to help people quit smoking (smoking cessation). Symptoms of depression include: Depressed mood – feeling sad, empty, or tearful.
What happens when you stop taking bupropion?
Neurological effects: You may experience tremors, restless legs, numbness, or difficulty walking. Psychological symptoms: You may experience mood swings, agitation, anxiety, mania, or depression. Brain zaps: This is a strange phenomenon that feels like a shock to your head.
How can I tell if Wellbutrin is working?
Your sleep, energy and appetite may start to improve in the first week or two. This can be an important sign that the drug is working. It often takes 6-8 weeks before you notice an improvement in your mood or regain interest in activities you enjoy.
What can you not take with bupropion?
Do not take bupropion with a monoamine oxidase (MAO) inhibitor (eg, isocarboxazid [Marplan®], linezolid [Zyvox®], phenelzine [Nardil®], selegiline [Eldepryl®], tranylcypromine [Parnate®]). Do not start taking bupropion during the 2 weeks after you stop a MAO inhibitor.
Is bupropion a stimulant?
Bupropion is an antidepressant with stimulant properties, which inhibits the reuptake of dopamine (DA) and norepinepherine, and is purported to enhance DA neurotransmission. Bupropion is considered an appealing candidate medication for the treatment of methamphetamine dependence.
What medications cause rapid weight loss?
Four weight-loss drugs have been approved by the U.S. Food and Drug Administration for long-term use:
- Bupropion-naltrexone (Contrave)
- Liraglutide (Saxenda)
- Orlistat (Xenical)
- Phentermine-topiramate (Qsymia)
Is bupropion good for anxiety?
found bupropion to be a safe and effective agent in the treatment of depression in the elderly. In addition to having a favorable side effect profile, bupropion has been shown to have positive results in treating anxiety associated with depression compared with sertraline and fluoxetine.
Can I take weight loss pills while on antidepressants?
Do not take over-the-counter slimming pills or fat-burners or any other herbal or pharmaceutical product that is advertised as a ‘sure-fire solution to rapid weightloss’ because many of these herbal products can interfere with your antidepressant treatment and even counteract the effect of your antidepressants leading …