Obesity may result in heart failure by inducing hemodynamic and myocardial changes that lead to cardiac dysfunction, or due to an increased predisposition to other heart failure risk factors.
How does obesity affect CHF?
Severe obesity was associated with a nearly fourfold higher risk of heart failure and about a twofold higher risk for both coronary heart disease and stroke compared with rates for those with a normal body mass index.
How does obesity lead to heart failure?
Obesity and overweight are also linked to hypertension and an enlarged left ventricle (left ventricular hypertrophy), increasing risk for heart failure. In addition, overweight and obesity can be related to some cancers, gallbladder disease and osteoarthritis.
Can obesity cause cardiomyopathy?
Obesity cardiomyopathy typically occurs in persons with severe and long-standing obesity. The predominant causes of death in those with obesity cardiomyopathy are progressive congestive heart failure and sudden cardiac death.
Does obesity cause an enlarged heart?
Summary: Excessive body weight is associated with left ventricular hypertrophy, a thickening of the heart muscle in the left ventricle, the heart’s pumping chamber. The largest study of its kind helps explain why excessive body weight increases the risk for heart disease.
How much does obesity contribute to heart disease?
High blood pressure is usually more frequent in obese people. A 10 kg higher body weight is associated with a 3.0 mm Hg higher systolic and 2.3 mm higher diastolic blood pressure; this increase estimates a 12% increase in coronary heart disease and 24% increased risk for stroke.
How does obesity affect heart rate?
The heavier you are, and the more fat you have on your body, the greater the strain on your heart. Obesity forces your heart to pump harder to distribute the blood throughout your body, and it causes your heart to beat faster.
How does obesity cause hypertension?
Obesity might lead to hypertension and cardiovascular disease by activating the renin–angiotensin–aldosterone system, by increasing sympathetic activity, by promoting insulin resistance and leptin resistance, by increased procoagulatory activity and by endothelial dysfunction.
Can obesity cause diastolic heart failure?
Obesity causes diastolic dysfunction, and is one of the leading causes of heart failure with preserved ejection fraction. Myocardial relaxation is determined by both active metabolic processes such as impaired energetic status and steatosis, as well as intrinsic myocardial remodelling.
Will losing weight help CHF?
People who lose weight actually improve their hearts by decreasing the thickness of the heart muscle, and that probably lowers their risk for heart failure, he added. Weight gain in the belly, where fat accumulates around the organs, may produce hormones that can harm the heart and cause inflammation, Neeland said.